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Among people diagnosed with Alzheimer’s, researchers recognize familial forms of the disease and sporadic cases. This shifting appreciation of inherited risk, researchers say, is due to a better understanding of the role of a fourth gene that carries the blueprints to make a lipid-carrying protein called apolipoprotein E, known as APOE. One known as APOE2 is thought to be protective against the development of Alzheimer’s disease. They also compared people with two copies of APOE4 to people with other inherited forms of the disease — early-onset autosomal dominant Alzheimer’s disease (ADAD) and Down syndrome-associated Alzheimer’s disease (DSAD). Gene testing isn’t currently recommendedIt is also likely to change how people who carry the APOE4 gene are diagnosed and treated.
Persons: APOE4, , Dr, Juan Fortea, Sant, Fortea, Charles Bernick, Bernick, Alzheimer’s wasn’t, isn’t, they’re, ” Fortea, Sanjay Gupta, Reisa Sperling, , ” Sperling, ” Dr, Sterling Johnson, Johnson Organizations: CNN, Nature, National Alzheimer’s Coordinating, Neurology, Hospital de, Cleveland Clinic Lou, Brain Health, CNN Health, Alzheimer’s Research, Brigham, Women’s, Alzheimer’s, University of Wisconsin Locations: Alzheimer’s, Spain, United States, Santa, Barcelona, Wisconsin
I wanted to set foot on the European and Asian side of Istanbul during a recent visit with my kids. A $1 commuter ferry was the cheapest option for us to go from the European side to the Asian side. The ride was only 20 minutes each way, and I was surprised not to see more tourists on the ferry. Plus, although they technically go through Asia, none of the cruises I found let passengers disembark in Asia. Instead of sitting inside, we made our way to the second level of the ferry and took seats on the rooftop deck.
Persons: , Jamie Davis Smith, I'm, We'd, we'd Organizations: Service, Cruises Locations: Istanbul, Asia, Europe, Eminonu, Istanbul's, Galata, Blue, Kadiköy, Istabul's
"I don't think they lack for anything that they need," Lyle Goldstein, director of Asia engagement at Defense Priorities, said of China's forces. Military forces are being deployed nearer to Taiwan than ever, effectively shortening Taiwan's reaction time. Stockpiling of China's rocket force, too, suggests it would have more than enough missiles and rockets to target Taiwan. One common concern is that as China's military exercises around Taiwan have grown in frequency and size, the line between exercise and potential attack is becoming blurred. Xie Huanchi/Xinhua via Getty ImagesExperts, as well as US and Taiwan lawmakers and military officials, have long debated about the readiness of the People's Liberation Army as China's military is known.
Persons: , Lyle Goldstein, Stringer China, Xi, Thomas Shugart, who's, Shugart, Goldstein, Mike Studeman, Xi Jinping, Dean Cheng, haven't, Cheng, Xie Huanchi, There's, Kyle Amonson, Dane Egli, Annabelle Chih, Getty Images Goldstein, Joe Biden Organizations: Service, Business, Defense, REUTERS, Taiwan's, Taiwan's Ministry of Defense, US Department of Defense, China Economic, Security, PLA, Patriot, US, Center, New, New American Security, Marine Corps, China Coast Guard, Scarborough, ROSA, Military, of Naval Intelligence, Pacific Command, US Institute of Peace, of, People, Getty Images, People's Liberation Army, CCP, Soviet, Center for Strategic, International Studies, Japan, US Coast Guard, Chinese Communist Party, Democratic Progressive Party, Kyodo, Stills Locations: China, Taiwan, Asia, Liaoning, Beijing, New American, AFP, Hong Kong, Xinhua, DoD's China, Cuba, US, Tainan, Japan, Philippines
I live in Victoria, Canada, and I think ferries are the best way to get to Seattle, Washington. There are passenger ferries and car ferries, so I tried both to see which is more worth it. Although it's nice to have a car if you want to do some shopping, I prefer the passenger ferry. The Victoria Clipper is a popular, high-speed passenger ferry that goes from harbor to harbor. This story is available exclusively to Business Insider subscribers.
Persons: , I'm Organizations: Service, Victoria Clipper, Ferries, Business Locations: Victoria, Canada, Seattle , Washington, British Columbia, Seattle ., Vancouver, Seattle
Let Them Eat … Everything
  + stars: | 2024-04-21 | by ( Lisa Miller | ) www.nytimes.com   time to read: +1 min
The sheet-pan chicken and roasted broccoli are out of the oven, and white rice is steaming on the stove. Sole-Smith tries not to be a short-order cook. “Respect the labor,” is how she puts it, reminding her children that if they don’t like what she has prepared, there’s other stuff to eat in the house. A pullout shelf in the pantry holds Tate’s chocolate chip cookies, Goldfish crackers, pea snaps, and chocolate kisses. A year ago, Sole-Smith published “Fat Talk: Parenting in the Age of Diet Culture,” a guide to helping parents grapple with their discomfort and anxiety about weight and food.
Persons: Smith, Violet, Beatrix, Penelope Organizations: Virginia Locations: Cold, N.Y
Courtesy Port Ellen DistilleryAcross the courtyard, the new still room resembles a vast industrial greenhouse with four shiny new copper stills as its exotic plants. “It is important that we recreate that classic Port Ellen character that people love, but we also want to be doing things we’ve not done before,” says McDonald. Courtesy Port Ellen DistilleryA glimpse into that past comes in the musky surroundings of warehouse number two with a dram drawn straight from a cask filled in 1979. Port Ellen is hoping to attract upscale whisky fans to sample a by-appointment-only Atlas of Smoke Experience. “At the moment, Port Ellen is expensive because it is so old and so rare.
Persons: Carol Ann Duffy’s, ” “, Ellen, , attar, Port Ellen, Roy Duff, Dramface.com, Ardbeg, Hijiri, Alexander McDonald, McDonald, Port, Port Ellen Gemini, Ellens, There’s, Dramface’s Duff, ” Emily Burnham, Organizations: Scotland CNN, Port, Ellen, Diageo, North America —, Smoke Locations: Islay, Scotland, Isle of Islay, Wuyi, Port, Scottish, , Highland, Brora, Falkirk, Scotland’s, Hong Kong, Kilnaughton Bay, Antrim, Northern Ireland, Mull, Kintyre, North, America, United States
CNN —A couple of African paradise islands have been on the radar of avid world travelers for some time. Shellfish Bay on the island’s windward side shelters one of East Africa’s most spectacular beaches, a crescent of white sand framed by 100-meter dunes. Bazaruto Island Resort, the island’s top digs, can arrange scuba diving and snorkeling, sailing on traditional dhow boats, guided 4x4 wildlife safaris, sandboarding on the dunes and other outdoor activities. Lamu’s best beaches are on the island’s windward side, around a 30–40-minute walk via Shela village. — and an ancient stone nilometer for measuring the river’s water level — reflect the island’s importance during pharaonic times.
Persons: São Filipe, Denis, Ponta, Ariadne Van Zandbergen, Dar es Organizations: CNN, Ethiopian Airways, oneworld, Getty, UNESCO, Heritage, Cabo Verde Airlines, Overseas, Paris Orly, Animalia Museum, Egypt, Vogue, Reserve, Dar es Salam Locations: Mauritius, Seychelles, Canary, Africa, Madagascar, Addis Ababa, Bazaruto, Mozambique, East, sandboarding, Johannesburg, Vilanculos, Lamu, Kenya, Manda, Malindi, Nairobi, JamboJet, Fogo, Cape Verde, Cabo Verde, West Africa, Pico, Verde’s, Praia, Overseas Territory, Réunion, French Caribbean, L’Hermitage, Saint, Paris, Antananarivo, Elephantine, Egypt, Aswan, Bissagos, Guinea, Bissau, Bubaque, Pemba, Tanzania, Zanzibar, Tanga, Dar, FlightLink
Some coastal cities are seeing ferry ridership bounce back after a decline during the pandemic, and growing interest in water transit is spurring both new types of ferry services and waterfront development. Carteret, N.J., is launching a ferry service to Manhattan, adjacent to a waterfront film and television production complex. Ferry service is also central to the development of a new community on a former naval base off San Francisco. Last year, the Federal Transit Administration announced grants totaling $220.2 million for ferry systems. And local governments are offering tax incentives to redevelop industrial zones.
Organizations: Puget Sound, Federal Transit Administration Locations: Bremerton, Wash, Seattle, Carteret, N.J, Manhattan, San Francisco
A small island controlled by Taiwan a few miles off China’s coast lived for decades in constant readiness for war. At one point in 1958, troops there hunkered in bunkers as Communist forces rained hundreds of thousands of shells on them. These days, the island, Kinmen, has become a hub of Taiwan’s commerce with China and its abandoned, weatherworn fortifications are tourist sites. Eight ferries a day take Taiwanese businesspeople and visitors from Kinmen to mainland China. But the sea around Kinmen has again turned tense after two Chinese men onboard a speedboat died in the area last month while trying to flee a Taiwanese Coast Guard vessel.
Organizations: Coast Guard Locations: Taiwan, Kinmen, China
I booked a deluxe cabin on an eight-hour ferry from Santorini to Athens. My upgraded cabin made it feel like I was traveling in a floating hotel room . AdvertisementI recently went on a short trip to Santorini from my home in Athens and decided to take a ferry both ways. But I upgraded to a 157-euro deluxe cabin for the ride back. Here's what my luxurious eight-hour trip was like.
Persons: Organizations: Service, Blue Star Ferries Locations: Santorini, Athens
I often take ferries around the Greek Islands , but Athen to Santorini was my longest journey yet. I traveled on a gray, rainy day, but the ferry was smooth and the views were still good. The ticket was only about $50, but I probably wouldn't do it again since flying is much faster. I recently booked an economy-class ticket on a Blue Star ferry from Athens to Santorini for 45 euros, or about $50. The nearly eight-hour journey was set to be my longest ferry ride to date.
Persons: Organizations: Service, Blue Star, Business Locations: Santorini, Athens, Greece
CNN —Thousands of residents have been evacuated in Plymouth, southwest England, as authorities work to remove an unexploded 500-kilogram (1,102-pound) bomb discovered in the city. Members of HM Coastguard Search and Rescue gather after homes were evacuated when a suspected WWII explosive device was discovered. Matt Keeble/PA Images/Getty ImagesThe bomb will then be disposed of at sea, Plymouth City Council said Friday. It was discovered in a garden in the city’s Keyham area. Authorities added that the city’s trainline would be closed, ferries suspended and buses diverted.
Persons: Michael, Matt Keeble, It’s, Phil Williams Organizations: CNN, Authorities, Ministry of Defence, Twitter, HM Coastguard, Plymouth City, Cornwall Police, Residents Locations: Plymouth, England, Keyham, Devon
Norway boasts the highest electric vehicle adoption rate in the world. Some 82% of new car sales were EVs in Norway in 2023, according to the Norwegian Road Federation (OFV). In comparison, 7.6% of new car sales were electric in the U.S. last year, according to Kelley Blue Book estimates. In the world's largest auto market, China, 24% of new car sales were EVs in 2023, according to the China Passenger Car Association. So that's a big advantage," said Petter Haugneland, the assistant secretary general of the Norwegian EV Association.
Persons: Kelley, Ragnhild Syrstad, Syrstad, Petter Haugneland Organizations: Norwegian Road Federation, China Passenger Car Association, Norwegian Ministry of, Norwegian EV Association . CNBC Locations: Norway, U.S, China, Norwegian, Oslo
Fires Are the Sum of Our Choices
  + stars: | 2024-02-14 | by ( David Wallace-Wells | ) www.nytimes.com   time to read: +2 min
In early February, the deadliest South American wildfires in a century swept through Valparaiso, Chile, killing more than a hundred people. In the United States, mercifully little land burned — only 2.6 million acres, which was less than half the recent average. But in Canada, fires ate through more than twice as much forest as the country’s previous modern record, the total burn scar large enough that more than half the world’s countries could fit inside. In Greece, one fire forced the country’s largest-ever evacuation, and another became the largest fire in the history of the European Union. And in the United States, especially, you increasingly hear a somewhat contrarian explanation that emphasizes fire suppression rather than warming.
Persons: , Stephen Pyne, Daniel Swain Organizations: European Union, Sydney Locations: Valparaiso, Chile, Lahaina, Maui, Hawaii’s, United States, Canada, Greece, Australia, McMurray , Alberta, Hawaii, Boulder County, Colo
It's one-fifth of the size of the lower 48 — the contiguous United States — and larger than California, Montana, and Texas combined. So unless you're planning an extended stay, focus on exploring a single region. If you want to see southeast Alaska and the Inside Passage, book a cruise or use a combination of planes and ferries to travel between cities. If you want to visit Denali National Park, then make Fairbanks — about a two-hour drive away from the entrance — your home base to explore the interior. And expect to mostly travel by plane if you want to go to Kodiak or Valdez and check out the Arctic.
Organizations: Fairbanks Locations: Mount, Alaska, United States, California , Montana, Texas, Kenai, Anchorage, Kodiak, Valdez
Hong Kong CNN —Thick roots tumble across a dilapidated house, the snake-like trunks of a banyan tree framing where the front door once stood. “These villages have existed in Hong Kong for hundreds of years, way before the colonial period,” explained Irvine. In the 1950s and ‘60s, as Hong Kong grew as an industrial hub, many people migrated to the rapidly expanding urban centers for better working opportunities. Stefan Irvine / Courtesy Blue Lotus Gallery, Hong Kong“There were calendars on the wall, school certificates in drawers — it’s quite poignant,” said Irvine. Stefan Irvine / Courtesy Blue Lotus Gallery, Hong KongHeritage valueWhile most of the villages Irvine photographed are abandoned, he was surprised to discover not all were.
Persons: Stefan Irvine, ” Irvine, “ It’s, , , Irvine, Wong Chuk, Lai Chi Wo, they’ll, Tung Ping Chau, Yim Tin Tsai, Luk Keng, Lai, they’ve, Hong, Wo Organizations: Hong Kong CNN, steely, Hong, HK, Irvine, Blue Lotus Locations: Hong Kong, Malaysian, India, Irvine, New Territories, Accounting, Hong Kong’s, London, Tai Peng, Lamma, Lai Chi, Queen's Hill, Fanling, Tung, Shenzhen, China, , Mau, Lai, Hong
AdvertisementThe key to budget travel in the Maldives is visiting the local islandsWe found visiting local islands to be a beautiful and affordable way to experience the true culture of the Maldives. AdvertisementThe local Maldivian Islands were affordable and beautifulThe local islands were stunning. These excursions proved the waters of the local islands had just as much to offer as the private-island resorts. By staying on the local islands, we got to experience more of the Maldivian cultureBecause we visited the local islands, we got to learn a lot about the local culture. By staying on the local islands, we got to interact with members of the community and learn about their incredible sea-faring history.
Persons: , Geena Truman, we'd, Truman Organizations: Service, Business, Manta Rays Locations: Maldives, Southeast Asia, Ukulhas, Omadhoo, Maldivian
Sydney CNN —“Australia Day is Dead!” Indigenous activist Gwenda Stanley chants into the loudspeaker, as a crowd of thousands breaks into applause. This is not a day to celebrate.”Nearby, Kevin Shaw-Taylor agrees January 26 is “absolutely not” an appropriate day for national celebrations. On the other side of the city, the Australia Day party was in full swing. A yacht sails in Sydney Harbor to mark Australia Day on January 16, 2024. Instead of guilt on Australia Day, a vast number of Australians “associate it with summer fun,” says Bongiorno, from the ANU.
Persons: Gwenda Stanley, It’s, Lynda, June Coe, Jenny Evans, , Grace, Elise, Kevin Shaw, Taylor, Arthur Phillip, Dan Himbrechts, EFE, Frank Bongiorno, , Asanka Ratnayake, Chelsea Watego, , Peter Dutton, ” Dutton, Dutton, Brad Banducci, Banducci, ” Banducci, Captain Cook, Queen Victoria, Queen, Diego Fedele, “ I’m, UQ’s, we’ve, we’re Organizations: Sydney CNN —, Indigenous, , CNN, Australia, First Nations, Sydney, British Royal Navy, Australian National University, ANU, Aboriginal, Torres Strait Islanders, Voters, Nations, Curumba, Sea, Indigenous Voice, Coalition, Woolworths, Sovereign Movement, Blak Locations: Sydney, “ Australia, Belmore, Sydney’s, Australia, Sydney Harbor, Melbourne, Queensland, Queen Victoria
Here are some of the best islands in Europe for getting away from almost everyone:Schiermonnikoog, the NetherlandsThe Netherlands is better known for canals, dikes and tropical Dutch Caribbean Islands like Bonaire and Curaçao than the sandspun isles along the country’s North Sea coast. Flores Island, Azores, PortugalWaterfalls trickle down an imposing rock face on the island Flores in the Azores. aroxopt/Adobe StockOne of the most remote islands in an already remote archipelago, Flores Island in the westernmost stretches of the Azores is a nature lover’s dream. To say there’s room to stretch out and breathe on these Baltic Sea islands is an understatement. The best islands in Europe for getting away from almost everyoneHavsVidden offers a secluded escape on northern Fasta Åland with villas with their own saunas overlooking the rocky shoreline.
Persons: Annemarieke Romeijn, , Eyrún, Gabriela Silva, Flores, Rocha dos Bordões, Santa Cruz das Flores, Randi Skaug, , Torunn Tronsvang, Richard Kellett, Luis Fonseca, iStockphoto, São João Baptista, Berlengas, Arlindo Serrao, Mola mola, Francesco Curione, Lent, Skyros, revelry, – it’s, Drake, Åland Organizations: CNN, Adobe, Heimaey, puffin, Norway Visitors, Intrepid, UNESCO, Visitors Locations: Europe, Ibiza, Netherlands, Caribbean, Bonaire, Curaçao, West Frisian, Wadden, Schier, Lauwersoog, Vestmannaeyjar, Iceland, Heimaey, Westman, Hotel Ranga, gannet, fulmar, Flores Island, Azores, Portugal, Flores, Santa Cruz, Naustholmen, Norway, Bodø, Northern Norway, Norwegian, Lofoten, , Tiree, Scotland, Hawaii, Scottish, Oban, Glasgow, Loganair, Berlengas, Peniche, São, Grande, Alicudi, Sicily, Italy, Taormina, Skyros, Greece, Mykonos, Rathlin, Northern Ireland, Ballycastle, Åland, Finland, Bothnia, Sweden
So how do you register to pay the fee if you’re just coming for the day? And how do you register an exemption if you’re staying overnight? Click on pay the fee – you’ll then be taken to a landing page run by Venezia Unica, the city’s official tourism site. If you’re a tourist, you’ll likely be applying because you’re staying overnight. You enter your details and select the place you're staying.
Persons: we’ll, Stanley Tucci, CNN —, It’s, they’ll, you’re, you’ll, Venezia Unica, You’ll, you’ve, , Piazzale Roma, Comune, ” It’ll, , you'll, Riva degli Schiavoni Organizations: CNN, intel, Piazzale Roma, Venezia, Comune, Venezia Santa Lucia, , , Venice, UNESCO Locations: Venice, Murano, City, Venezia Santa, Mestre
Asia markets set to rebound from Tuesday's broad sell-off
  + stars: | 2023-12-06 | by ( Lim Hui Jie | ) www.cnbc.com   time to read: 1 min
Sydney Harbour taking in the Harbour Bridge, Opera House and ferries at sunrise during the COVID-19 pandemic on April 20, 2020 in Sydney, Australia. Asia-Pacific markets rebounded across the region, following a broad sell-off on Monday. Wednesday will see Australia release its third-quarter GDP numbers, while investors will also digest the Reuters Tankan survey for Japan in December, which showed improving business sentiment among large Japanese manufacturers. The Tankan survey, done by the Bank of Japan quarterly, measures economic conditions in Japan and the survey results are considered a key economic indicator. The Reuters monthly poll is considered to be a leading indicator of the BOJ's official survey.
Organizations: Sydney Harbour, Opera House, Reuters, Bank of Japan Locations: Sydney, Australia, Asia, Pacific, Japan
The X Shore Pro, which is meant for commercial operations or coast guards, is based on the former and shares most of its specifications. The X Shore 1 costs upwards of €109,000 (about $119,000), but the more expensive models in the lineup start at €195,000 (about $213,000). According to Keisu, the experience of riding an X Shore boat is radically different to a traditional one. “The only difference is that we [X Shore] use our batteries also for propulsion, so we have much larger battery packs,” she says. However, technological constraints may be slowing down the electrification of boats, including small leisure boats such as those manufactured by X Shore.
Persons: that’s, Tesla, , Maria Niläng, we’re, X Shore, Jenny Keisu, X, Keisu, Timothy McCoy, McCoy, ” Brandon Taravella, , ” Keisu Organizations: CNN, X Shore, Värmdö Archipelago, University of Michigan, University of New, UNESCO Locations: Stockholm, Sweden, Swedish, Värmdö, X, University of New Orleans, Norway
Cruise crew members are accusing Carnival UK of threatening to "fire and rehire" 919 of them. A maritime union said Carnival UK filed a notice of mass layoffs as it was negotiating pay cuts. The entire dispute stems from negotiations between Carnival UK and Nautilus over potential pay cuts. Carnival UK is run by the Carnival Corporation group, which also operates Carnival Cruise Line, the US cruise company. AdvertisementNovember 24, 2023: This story was updated to reflect comment from Carnival UK.
Persons: Organizations: Carnival, Service, Nautilus International, O Ferries, Unions, Nautilus, O Cruises, Cunard, O, BBC, Carnival UK's, Carnival Corporation, Cruise, Princess Cruises, O Cruises Australia, Carnival UK
(Reuters) - A Ukrainian sea drone attack on Russia's Crimean bridge in July had "overturned" naval operations and forced Moscow to resort to ferries to move weaponry, the head of Ukraine's main intelligence agency said in a video broadcast on Friday. "We have practically overturned the philosophy of naval operations," Maliuk said in the first of a series of televised documentaries entitled "SBU, the Special Operations of Victory." Plenty of surprises lie ahead and not just the Crimean bridge." Traffic has since been operating on the bridge, though Russian officials say repair work is still proceeding. The attack on the bridge is one of a number of Ukrainian offensive actions in the Black Sea, including a missile assault on the Black Sea Fleet headquarters in Sevastopol in September.
Persons: Vasyl Maliuk, Maliuk, Volodymyr Zelenskiy, Zelenskiy, Ron Popeski, Oleksandr Kozhukhar, Josie Kao Organizations: Reuters, Security Service of Ukraine, Black, Fleet Locations: Ukrainian, Moscow, Kyiv, Russia, Russian, Sevastopol, Ukraine
Newly appointed Head of the Ukraine's State Security Service Vasyl Maliuk looks on during a session of Ukrainian parliament, amid Russia's attack on Ukraine, in Kyiv, Ukraine February 7, 2023. Ukrainian Presidential Press Service/Handout via REUTERS/File Photo Acquire Licensing RightsNov 24 (Reuters) - A Ukrainian sea drone attack on Russia's Crimean bridge in July had "overturned" naval operations and forced Moscow to resort to ferries to move weaponry, the head of Ukraine's main intelligence agency said in a video broadcast on Friday. "We have practically overturned the philosophy of naval operations," Maliuk said in the first of a series of televised documentaries entitled "SBU, the Special Operations of Victory." Traffic has since been operating on the bridge, though Russian officials say repair work is still proceeding. Zelenskiy said this month that Ukraine has seized the initiative from Russia in the Black Sea and, thanks to the use of naval drones, forced Russia's naval fleet and warships to pull back.
Persons: Ukraine's State Security Service Vasyl Maliuk, Vasyl Maliuk, Maliuk, Volodymyr Zelenskiy, Zelenskiy, Ron Popeski, Oleksandr Kozhukhar, Josie Kao Organizations: Ukraine's State Security Service, Presidential Press Service, REUTERS, Security Service of Ukraine, Black, Fleet, Thomson Locations: Ukraine's, Ukraine, Kyiv, Ukrainian, Moscow, Russia, Russian, Sevastopol
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